白癜风怎麽治 https://m-mip.39.net/pf/mipso_6159813.html摘要:肿瘤科常用治疗方案简介-紫杉醇/卡铂方案(1)。
★★一、紫杉醇/卡铂方案在恶性肿瘤中的剂量及用法
★1.乳腺癌
◆1.卡铂+紫杉醇+曲妥珠单抗(TCbH方案-三周方案)
卡铂AUC6d1每21天重复;
紫杉醇mg/m2d1;
曲妥珠单抗初始4mg/Kg,后续2mg/Kgd1每7天重复;
或初始8mg/Kg,后续6mg/Kgd1每21天重复。
来源:CSCO乳腺癌指南
◆2.卡铂+紫杉醇+曲妥珠单抗(TCbH方案-单周方案)
卡铂AUC2d1每7天重复;
紫杉醇80mg/m2d1;
曲妥珠单抗初始4mg/Kg,后续2mg/Kgd1每7天重复;
或初始8mg/Kg,后续6mg/Kgd1每21天重复。
来源:CSCO乳腺癌指南
◆3.Paclitaxel/carboplatin+trastuzumab
CarboplatinAUC6IVday1;
Paclitaxelmg/m2IVday1;
Cycledevery21days.
Trastuzumab4mg/kgIVday1followedby2mg/kgIVweekly;
orTrastuzumab8mg/kgIVday1followedby6mg/kgIVday1every21days.
来源:-4版NCCN乳腺癌指南
◆4.Weeklypaclitaxel/carboplatin+trastuzumab
Paclitaxel80mg/m2IVdays1,8,and15;
CarboplatinAUC2IVdays1,8,and15;
Cycledevery28days.
Trastuzumab4mg/kgIVday1followedby2mg/kgIVweekly;orTrastuzumab8mg/kgIVday1followedby6mg/kgIVday1every21days.
来源:-4版NCCN乳腺癌指南
◆5.Carboplatin/paclitaxel
Paclitaxel–mg/m2IVday1;
CarboplatinAUC6IVday1;
Cycledevery21days;
orPaclitaxelmg/m2IVdays1,8,and15;
CarboplatinAUC2IVdays1,8,and15;
Cycledevery28days.
来源:-4版NCCN乳腺癌指南
★2.卵巢癌
◆1.紫杉醇+卡铂
紫杉醇mg/m2静脉滴注3小时第1天;
随后卡铂AUC5-6静脉滴注1小时第1天;
每3周重复。
来源:CSCO卵巢癌指南
◆2.紫杉醇+卡铂+贝伐珠单抗
适用于卵巢癌II-IV期
紫杉醇mg/m2静脉滴注3小时第1天;
随后卡铂AUC5-6静脉滴注1小时第1天;
贝伐珠单抗7.5mg/m2静脉滴注30-90分钟第1天;
每3周重复,共6周期,之后贝伐珠单抗单药维持12周期。
来源:CSCO卵巢癌指南
◆3.Paclitaxel/carboplatin
?Paclitaxelmg/m2IVfollowedbycarboplatinAUC5–6IVDay1;
?Repeatevery21daysx3–6cycles.
来源:-1版NCCN卵巢癌指南
◆4.Paclitaxelweekly/carboplatinq3weeks
?Dose-densepaclitaxel80mg/m2IVDays1,8,and15;
followedbycarboplatinAUC5–6IVDay1;
?Repeatevery21daysx6cycles
来源:-1版NCCN卵巢癌指南
◆5.Paclitaxelweekly/carboplatinweekly
?Paclitaxel60mg/m2IVfollowedbycarboplatinAUC2IV
?Days1,8,and15;repeatevery21daysx6cycles(18weeks).
来源:-1版NCCN卵巢癌指南
◆6.Paclitaxel/carboplatin(适用于ElderlyPatients(age70years)and/orthosewith